Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342946 | 0.79 | P2RX4 (0.46) | BCHEGAASMN1; SMN2SCN9A | |
| SCHEMBL7433336 | 0.76 | GAA (0.38) | BCHEGAASMN1; SMN2 | |
| SCHEMBL20013878 | 0.72 | BCHE (0.62) | BCHEMAPK1KDM1AGAASMN1; SMN2 | |
| SCHEMBL4253863 | 0.72 | BCHE (0.57) | BCHEMAPK1KDM1AGPR119 | |
| SCHEMBL6255939 | 0.71 | BCHE (0.46) | BCHEMAPK1KDM1ASMN1; SMN2GPR119 | |
| SCHEMBL5670700 | 0.71 | BCHE (0.46) | BCHEMAPK1KDM1AGPR119HDAC1 | |
| SCHEMBL5172363 | 0.71 | BCHE (0.46) | BCHEMAPK1KDM1ASMN1; SMN2GPR119 | |
| SCHEMBL6583411 | 0.69 | MAPK1 (0.49) | BCHEMAPK1KDM1AGPR119EPHX2 | |
| SCHEMBL7183324 | 0.69 | BCHE (0.43) | BCHEMAPK1KDM1AGPR119HDAC1 | |
| SCHEMBL3459528 | 0.67 | BCHE (0.48) | BCHEMAPK1KDM1ASMN1; SMN2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659017-B | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2026-05-15 | — | — | CN | disclosed |