Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172363 | 0.74 | BCHE (0.46) | BCHEKDM1AGRM5GRM1GPR119 | |
| SCHEMBL27928991 | 0.70 | BCHE (0.44) | BCHEKDM1AGRM5GRM1GPR119 | |
| SCHEMBL4253863 | 0.70 | BCHE (0.57) | BCHEKDM1AGPR119MAPK1 | |
| SCHEMBL6255939 | 0.69 | BCHE (0.46) | BCHEKDM1AGPR119HDAC1HDAC6 | |
| SCHEMBL5670700 | 0.69 | BCHE (0.46) | BCHEKDM1AGRM5GRM1GPR119 | |
| SCHEMBL38658293 | 0.69 | BCHE (0.46) | BCHEKDM1AGRM5GRM1GPR119 | |
| SCHEMBL3459528 | 0.65 | BCHE (0.48) | BCHEKDM1AGPR119HDAC1HDAC6 | |
| SCHEMBL7020597 | 0.65 | BCHE (0.44) | BCHEKDM1AGRM5GRM1GPR119 | |
| SCHEMBL9655258 | 0.64 | KDM4E (0.46) | MEN1KMT2A | |
| SCHEMBL6994927 | 0.64 | BCHE (0.43) | BCHEKDM1AGRM5GRM1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003031376-A1 | SOLID PHASE SYNTHESIS OF SUBSTITUTED 1,5-BENZODIAZEPINE-2-ONE AND 1,5-BENZOTHIAZEPINE-2-ONE | AVENTIS PHARMACEUTICALS INC. (US) | 2003-04-17 | — | — | WO | disclosed |