Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982062 | 0.87 | GAA (0.58) | GAASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL7981185 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1LMNAMAPTGRM5 | |
| SCHEMBL7978483 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1LMNAMAPTGRM5 | |
| SCHEMBL30660992 | 0.83 | GAA (0.47) | GAASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL24190643 | 0.83 | GAA (0.47) | GAASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL27242800 | 0.78 | SMN1; SMN2 (0.48) | GAASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL27242721 | 0.78 | SMN1; SMN2 (0.48) | GAASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL38660025 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1LMNAMAPTGRM5 | |
| SCHEMBL11453714 | 0.77 | SMN1; SMN2 (0.47) | GAASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9432301 | 0.76 | NOTUM (0.42) | GAASMN1; SMN2ALDH1A1GRM5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659017-B | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2026-05-15 | — | — | CN | disclosed |