Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194222 | 0.90 | S1PR1 (0.47) | S1PR1S1PR3S1PR5SIGMAR1CES1 | |
| SCHEMBL3194214 | 0.90 | S1PR1 (0.47) | S1PR1S1PR3S1PR5SIGMAR1CES1 | |
| SCHEMBL385864 | 0.86 | S1PR1 (0.44) | S1PR1S1PR3S1PR5SIGMAR1CTSK | |
| SCHEMBL385489 | 0.84 | S1PR1 (0.43) | S1PR1S1PR3S1PR5SIGMAR1CTSK | |
| SCHEMBL386963 | 0.82 | FAAH (0.36) | SIGMAR1CTSKCES1 | |
| SCHEMBL386136 | 0.81 | S1PR1 (0.44) | S1PR1S1PR3S1PR5SIGMAR1CES1 | |
| SCHEMBL386135 | 0.81 | S1PR1 (0.44) | S1PR1S1PR3S1PR5SIGMAR1CES1 | |
| SCHEMBL386686 | 0.81 | S1PR1 (0.43) | S1PR1S1PR3S1PR5SIGMAR1CTSK | |
| SCHEMBL3194642 | 0.80 | S1PR1 (0.46) | S1PR1S1PR3S1PR5SIGMAR1CES1 | |
| SCHEMBL3194650 | 0.80 | S1PR1 (0.46) | S1PR1S1PR3S1PR5SIGMAR1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101650-B2 | Method for treating a immunology-related disease | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8067396-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2011-11-29 | — | — | US | disclosed |