Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295218 | 0.79 | NR1H4 (0.42) | NR1H4LMNAMAPTMEN1PLIN1 | |
| SCHEMBL38659096 | 0.76 | KDM4E (0.32) | LMNAMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL38660353 | 0.74 | ALDH1A1 (0.47) | LMNAMAPTMEN1PLIN1POLB | |
| SCHEMBL27537188 | 0.74 | NR1H4 (0.67) | NR1H4LMNAMAPTMEN1KMT2A | |
| SCHEMBL27252480 | 0.74 | CCNB2 (0.47) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL16303657 | 0.74 | CCNB2 (0.47) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL14608164 | 0.73 | MEN1 (0.46) | LMNAMAPTMEN1PLIN1POLB | |
| SCHEMBL38659438 | 0.73 | ERN1 (0.49) | LMNAMAPTNPC1HPGDRAB9A | |
| SCHEMBL25240005 | 0.71 | MEN1 (0.41) | LMNAMAPTMEN1PLIN1POLB | |
| SCHEMBL14653903 | 0.71 | MAPT (0.41) | LMNAMAPTMEN1PLIN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102212-A1 | MACROCYCLIC MCL-1 INHIBITORS | VANDERBILT UNIVERSITY (US) | 2026-05-15 | — | — | WO | disclosed |