SCHEMBL38659563

SCHEMBL38659563

O=C(O)CCc1cc(O)ccc1-c1ccc(-c2cccc(C(F)(F)F)c2)c(CF)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 0.44
▸ RXRB P28702 1/20 0.44
▸ RXRG P48443 1/20 0.44
▸ PTGER4 P35408 3/20 0.44
▸ PTGER3 P43115 3/20 0.44
▸ PTGER1 P34995 2/20 0.44
▸ PTGER2 P43116 2/20 0.44
▸ CTSK P43235 1/20 0.43
▸ FFAR1 O14842 5/20 0.43
▸ FFAR4 Q5NUL3 3/20 0.42
▸ MME P08473 1/20 0.42
▸ MCL1 Q07820 1/20 0.41
▸ SLC13A5 Q86YT5 1/20 0.41
▸ PTGDR2 Q9Y5Y4 1/20 0.41
▸ THRA P10827 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ AKR1C3 P42330 1/20 0.40
▸ AKR1C2 P52895 1/20 0.40
▸ MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1891430 1.00 RXRA (0.44) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL1896247 0.91 RXRA (0.44) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL1893748 0.88 SLC1A3 (0.47) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL38659906 0.88 SLC1A3 (0.47) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL35843126 0.86 MME (0.42) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL1890265 0.86 MME (0.42) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL1810928 0.86 KDM4E (0.45) MCL1AKR1C3AKR1C2MAPT
SCHEMBL1895197 0.85 AKR1C3 (0.44) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL1811354 0.84 FFAR1 (0.50) RXRARXRBRXRGPTGER4PTGER3
SCHEMBL38659420 0.84 FFAR1 (0.50) RXRARXRBRXRGPTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099533-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) WITH GPBP1 INHIBITORS UNIVERSITAT DE VALÈNCIA (ES) 2026-05-15 — — WO claimed
WO-2026099533-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) WITH GPBP1 INHIBITORS UNIVERSITAT DE VALÈNCIA (ES) 2026-05-15 — — WO disclosed
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