Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863591 | 0.94 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL3863596 | 0.86 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL3864057 | 0.79 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL5616930 | 0.78 | TLR7 (0.77) | TLR7TLR8 | |
| SCHEMBL3864055 | 0.78 | TLR7 (0.48) | TLR7TLR8 | |
| SCHEMBL3863594 | 0.77 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL3864062 | 0.77 | TLR7 (0.48) | TLR7TLR8 | |
| SCHEMBL4871874 | 0.76 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL4864847 | 0.76 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL4871871 | 0.76 | TLR7 (0.52) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023722-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023722-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | IFNG, IRF3, EIF2AK2 | TLR7 30/4885TLR8 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.