Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38659187 | 0.88 | USP2 (0.46) | GPR119HPGDUSP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6152989 | 0.84 | USP2 (0.47) | GPR119HPGDUSP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7065136 | 0.80 | GPR119 (0.48) | GPR119HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL1830482 | 0.80 | HPGD (0.48) | GPR119HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL8242595 | 0.80 | USP2 (0.61) | HPGDUSP2SMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL393481 | 0.78 | HPGD (0.46) | GPR119HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL28891296 | 0.78 | GPR119 (0.46) | GPR119HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL14450372 | 0.78 | HPGD (0.46) | GPR119HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL1652860 | 0.78 | USP2 (0.42) | GPR119HPGDUSP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL38660442 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102212-A1 | MACROCYCLIC MCL-1 INHIBITORS | VANDERBILT UNIVERSITY (US) | 2026-05-15 | — | — | WO | disclosed |