SCHEMBL38660959

SCHEMBL38660959

COC(=O)[C@H](Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 2/20 0.56
MAPT P10636 3/20 0.53
KDM4E B2RXH2 2/20 0.53
APAF1 O14727 1/20 0.53
POLB P06746 1/20 0.53
RECQL P46063 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
CDK4 P11802 1/20 0.52
ECE1 P42892 1/20 0.52
HCRTR1 O43613 1/20 0.52
LMNA P02545 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GAA P10253 1/20 0.51
MIF P14174 1/20 0.51
MPO P05164 1/20 0.50
TSHR P16473 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15743162 0.90 TACR1 (0.58) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL28014888 0.90 TACR1 (0.58) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL15743161 0.90 TACR1 (0.58) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL31619542 0.90 TACR1 (0.58) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL9584638 0.88 TACR1 (0.59) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL23027210 0.88 TACR1 (0.62) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL25060309 0.88 TACR1 (0.62) TACR1MAPTKDM4EAPAF1POLB
Hydrochloric Acid SCHEMBL9584788 0.88 TACR1 (0.58) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL29577049 0.87 TACR1 (0.53) TACR1MAPTKDM4EAPAF1POLB
SCHEMBL22654030 0.87 SMN1; SMN2 (0.60) TACR1MAPTKDM4EAPAF1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122030505-A Use of TRPM8 inhibitors for improving animal productivity in cold conditions and method 中国科学院动物研究所 2026-05-15 CN disclosed