Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.62 |
| ▸ | NMBR | P28336 | 2/20 | 0.53 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060309 | 1.00 | TACR1 (0.62) | TACR1NMBRLNPEPSMN1; SMN2MAPT | |
| SCHEMBL31619542 | 0.90 | TACR1 (0.58) | TACR1SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL38660959 | 0.88 | TACR1 (0.56) | TACR1SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL22654031 | 0.87 | SMN1; SMN2 (0.60) | TACR1SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL22654030 | 0.87 | SMN1; SMN2 (0.60) | TACR1SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL12818038 | 0.87 | SMN1; SMN2 (0.60) | TACR1SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL27871525 | 0.82 | TACR1 (0.60) | TACR1NMBRLNPEPSMN1; SMN2MAPT | |
| SCHEMBL28503689 | 0.81 | TACR1 (0.56) | TACR1NMBRLNPEPSMN1; SMN2MAPT | |
| SCHEMBL28503688 | 0.81 | TACR1 (0.56) | TACR1NMBRLNPEPSMN1; SMN2MAPT | |
| SCHEMBL28514266 | 0.81 | TACR1 (0.56) | TACR1NMBRLNPEPSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | ADH5, HDHD5, ADH1A | TACR1 4624/4885NMBR 2324/4885LNPEP 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.