SCHEMBL38663293

SCHEMBL38663293

Cc1cccc(C)c1OC(=O)c1c2ccccc2nc2ccc(Br)cc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOR2 Q9Y618 2/20 0.45
RXFP1 Q9HBX9 2/20 0.45
PRNP P04156 1/20 0.45
PPARG P37231 1/20 0.45
NR2E3 Q9Y5X4 1/20 0.45
ALDH1A1 P00352 4/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.42
HDAC3 O15379 1/20 0.41
APP P05067 1/20 0.41
ACHE P22303 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1054774 0.88 MEN1 (0.49) ALDH1A1HTTSMN1; SMN2L3MBTL1MEN1
SCHEMBL38661829 0.88 MEN1 (0.49) ALDH1A1HTTSMN1; SMN2L3MBTL1MEN1
SCHEMBL7048368 0.86 MEN1 (0.45) RXFP1ALDH1A1SMN1; SMN2L3MBTL1MEN1
SCHEMBL38664805 0.84 PLA2G2A (0.49) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL13632698 0.81 MEN1 (0.45) RXFP1ALDH1A1SMN1; SMN2L3MBTL1MEN1
SCHEMBL7045178 0.80 KMT2A (0.48) ALDH1A1HTTSMN1; SMN2MEN1KMT2A
SCHEMBL38663303 0.79 PLA2G2A (0.50) ALDH1A1MEN1KMT2AMAPT
SCHEMBL7047710 0.78 MAPT (0.45) ALDH1A1HTTSMN1; SMN2MEN1KMT2A
SCHEMBL38663373 0.78 PDE10A (0.49) ALDH1A1HTTSMN1; SMN2MEN1KMT2A
SCHEMBL38661527 0.78 MEN1 (0.51) RXFP1ALDH1A1SMN1; SMN2L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099510-A1 RESILIENT MARKER COMPOUNDS MINTON, TREHARNE & DAVIES LIMITED (GB) 2026-05-15 WO disclosed