Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.60 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272228 | 0.86 | PSMB8 (0.51) | PARP1PSMB8NUDT1ADORA1ADORA3 | |
| SCHEMBL20252448 | 0.83 | PSMB8 (0.49) | PARP1PSMB8NUDT1ADORA1ADORA3 | |
| SCHEMBL20900188 | 0.80 | PARP1 (0.60) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL20900183 | 0.80 | PARP1 (0.60) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL28810281 | 0.75 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3092602 | 0.75 | PARP1 (1.00) | PARP1 | |
| SCHEMBL28809289 | 0.75 | PARP1 (1.00) | PARP1 | |
| SCHEMBL8265192 | 0.73 | PARP1 (0.59) | PARP1PSMB8NUDT1ADORA1ADORA3 | |
| SCHEMBL215756 | 0.73 | NUDT1 (0.70) | PSMB8NUDT1ADORA1ADORA3MGAM | |
| SCHEMBL1170768 | 0.72 | ADORA1 (0.61) | PARP1PSMB8NUDT1ADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |