Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.33 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16290592 | 0.92 | LOX (0.44) | LOXLOXL2S1PR1ALOX5APFEN1 | |
| SCHEMBL558400 | 0.92 | LOX (0.47) | LOXLOXL2S1PR1ALOX5APFEN1 | |
| SCHEMBL14881863 | 0.81 | AKT1 (0.39) | — | |
| SCHEMBL14881861 | 0.81 | AKT1 (0.39) | — | |
| SCHEMBL14896647 | 0.81 | AKT1 (0.39) | — | |
| SCHEMBL38661308 | 0.76 | S1PR1 (0.43) | LOXLOXL2S1PR1ELOVL1NAE1 | |
| SCHEMBL16290804 | 0.73 | CDK2 (0.37) | ALOX5APFEN1CA2CHKAMCHR1 | |
| SCHEMBL10188104 | 0.71 | ALDH1A1 (0.39) | ALOX5APFEN1CA2CHKAASIC3 | |
| SCHEMBL18615427 | 0.71 | JAK3 (0.39) | LOXLOXL2S1PR1NAE1UBA3 | |
| SCHEMBL29026979 | 0.71 | LOX (0.53) | LOXLOXL2ASIC3KCNH2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |