SCHEMBL38664985

SCHEMBL38664985

COC(C(=O)Nc1c(C)cncc1C(=O)O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.48
▸ ALDH1A1 P00352 4/20 0.48
▸ GAA P10253 3/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ PKM P14618 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ GLS O94925 4/20 0.44
▸ MAPT P10636 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ EIF2S1 P05198 1/20 0.43
▸ RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38663306 0.77 KDM4E (0.48) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL38666073 0.77 KDM4E (0.48) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL38664431 0.76 KDM4E (0.47) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL14818785 0.74 ALDH1A1 (0.57) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL38663113 0.72 KDM6B (0.56) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL38663305 0.72 ALDH1A1 (0.54) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL38666751 0.72 KDM4E (0.45) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL8049390 0.71 ALDH1A1 (0.77) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL13434151 0.69 ALDH1A1 (0.64) LMNAALDH1A1GAAL3MBTL1KMT2A
SCHEMBL8281830 0.69 ALDH1A1 (0.64) LMNAALDH1A1GAAL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104679-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 — — WO disclosed
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