⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29618892 | 0.78 | — | — | |
| SCHEMBL371953 | 0.78 | — | — | |
| SCHEMBL27654856 | 0.77 | CYP11B1 (0.40) | — | |
| SCHEMBL2605772 | 0.67 | CYP17A1 (0.36) | — | |
| SCHEMBL16822027 | 0.62 | AOC3 (0.38) | — | |
| SCHEMBL14291273 | 0.62 | CYP17A1 (0.31) | — | |
| SCHEMBL22548088 | 0.62 | CYP17A1 (0.46) | — | |
| SCHEMBL1132433 | 0.62 | — | — | |
| SCHEMBL2324216 | 0.62 | FEN1 (0.30) | — | |
| SCHEMBL25596755 | 0.62 | PLA2G7 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107377-A1 | PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL | KARANICOLAS JOHN (US) | 2026-05-21 | — | — | WO | disclosed |