Caffeic Acid Phenethyl Ester

Caffeic Acid Phenethyl Ester

SCHEMBL38666014

O=C(/C=C/c1ccc(O)c(O)c1)OCCc1ccccc1.O=C(O)/C=C/c1ccc(O)c(O)c1

nearest known ligand 0.93

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 5/20 0.93
AKR1B10 O60218 5/20 0.93
AKR1B1 P15121 5/20 0.93
APP P05067 5/20 0.93
CYP3A4 P08684 2/20 0.93
ALOX15 P16050 2/20 0.93
ALOX12 P18054 2/20 0.93
MAPK1 P28482 2/20 0.93
HSD17B10 Q99714 2/20 0.93
ALOX5 P09917 2/20 0.93
KDM4E B2RXH2 1/20 0.93
MEN1 O00255 1/20 0.93
GMNN O75496 1/20 0.93
ALDH1A1 P00352 1/20 0.93
EGFR P00533 1/20 0.93
LMNA P02545 1/20 0.93
ESR1 P03372 1/20 0.93
ERBB2 P04626 1/20 0.93
LCK P06239 1/20 0.93
FYN P06241 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Caffeic Acid Phenethyl Ester SCHEMBL490546 0.96 AKR1B10 (1.00) TTRAKR1B10AKR1B1APPCYP3A4
Caffeic Acid Phenethyl Ester SCHEMBL93649 0.96 AKR1B10 (1.00) TTRAKR1B10AKR1B1APPCYP3A4
Caffeic Acid Phenethyl Ester SCHEMBL28294426 0.96 AKR1B10 (1.00) TTRAKR1B10AKR1B1APPCYP3A4
Caffeic Acid Phenethyl Ester SCHEMBL30070826 0.96 AKR1B10 (1.00) TTRAKR1B10AKR1B1APPCYP3A4
Caffeic Acid Phenethyl Ester SCHEMBL30695557 0.95 TTR (0.97) TTRAKR1B10AKR1B1APPCYP3A4
Caffeic Acid Phenethyl Ester SCHEMBL15378852 0.91 APP (0.90) TTRAKR1B10AKR1B1APPCYP3A4
SCHEMBL2602741 0.89 APP (0.85) TTRAKR1B10AKR1B1APPCYP3A4
Caffeic Acid SCHEMBL2483116 0.88 TTR (0.72) TTRAKR1B10AKR1B1APPCYP3A4
Caffeic Acid SCHEMBL2483109 0.88 TTR (0.72) TTRAKR1B10AKR1B1APPCYP3A4
SCHEMBL20604716 0.88 APP (0.83) TTRAKR1B10AKR1B1APPCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056924-A Calcium alginate microsphere containing chitosan oligosaccharide coated bifidobacterium and caffeic acid phenethyl ester-loaded nano enzyme and preparation method thereof 重庆医科大学 2026-05-19 CN disclosed