Pyridine

Pyridine

SCHEMBL3867441

C1CCOC1.F.c1ccncc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 1/20 0.47
KCNA5 P22460 1/20 0.31
KCNH2 Q12809 1/20 0.31
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL6517120 1.00 TSHR (0.53) TSHRNAPRTTDP1ALDH1A1KCNA5
Pyridine SCHEMBL8505767 1.00 TSHR (0.53) TSHRNAPRTTDP1ALDH1A1KCNA5
Pyridine SCHEMBL845238 1.00 TSHR (0.53) TSHRNAPRTTDP1ALDH1A1KCNA5
Pyridine SCHEMBL22472321 0.97 TSHR (0.50) TSHRNAPRTTDP1ALDH1A1KCNA5
Pyridine SCHEMBL1546704 0.97 TSHR (0.50) TSHRNAPRTTDP1ALDH1A1KCNA5
Pyridine SCHEMBL3446743 0.97 TSHR (0.50) TSHRNAPRTTDP1ALDH1A1KCNA5
Pyridine SCHEMBL28203361 0.95 TSHR (0.47) TSHRNAPRTTDP1ALDH1A1KCNA5
Pyridine SCHEMBL10387368 0.95 TSHR (0.47) TSHRNAPRTTDP1ALDH1A1
Pyridine SCHEMBL8666898 0.90 TSHR (0.43) TSHRNAPRTTDP1ALDH1A1KCNA5
Dioxane SCHEMBL262902 0.88 TSHR (0.60) TSHRNAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697431-B1 BORON-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME SHOWA DENKO KK (JP) 2014-07-30 EP disclosed
US-7510782-B2 Boron-containing polymer compound and organic light emitting device using the same SHOWA DENKO K.K. (JP) 2009-03-31 US disclosed
US-20070167588-A1 Boron-containing polymer compound and organic light emitting device using the same SHOWA DENKO K.K. (JP) 2007-07-19 US disclosed
EP-1697431-A1 BORON-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME SHOWA DENKO KABUSHIKI KAISHA (JP) 2006-09-06 EP disclosed
WO-2005061562-A1 BORON-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME SHOWA DENKO K.K. (JP) 2005-07-07 WO disclosed
EP-0428286-B1 24- and 25-substituted avermectin and milbemycin derivatives MERCK & CO INC (US) 2000-04-05 EP disclosed
EP-0411897-B1 Avermectin derivatives MERCK & CO INC (US) 1998-12-02 EP disclosed
US-5830875-A PARASITICIDES MERCK & CO., INC. (US) 1998-11-03 US disclosed
US-5240915-A Anthelmintics, parasiticides MERCK & CO., INC. (US) 1993-08-31 US disclosed
US-5208222-A Anthelemetic MERCK & CO., INC. (US) 1993-05-04 US disclosed
EP-0506331-A1 4\"-and 4'-alkylthio-avermectin derivatives MERCK & CO. INC. (US) 1992-09-30 EP disclosed
EP-0456509-A1 Derivatives of 3' - and 3\"-0-desmethyl avermectin compounds MERCK & CO. INC. (US) 1991-11-13 EP disclosed
US-5057499-A Parasiticides MERCK & CO. INC. (US) 1991-10-15 US disclosed
US-5023241-A Parasiticides, anthelmintic, insecticides, miticides MERCK & CO., INC. (US) 1991-06-11 US disclosed
EP-0428286-A2 24- and 25-substituted avermectin and milbemycin derivatives MERCK & CO. INC. (US) 1991-05-22 EP disclosed
EP-0411897-A2 Avermectin derivatives MERCK & CO. INC. (US) 1991-02-06 EP disclosed
EP-0400975-A2 Avermectin derivatives MERCK & CO. INC. (US) 1990-12-05 EP disclosed
EP-0375393-A1 Avermectin derivatives MERCK & CO. INC. (US) 1990-06-27 EP disclosed
EP-0375395-A2 Derivatives of 3'-and 3\"-0-desmethyl avermectin compounds MERCK & CO. INC. (US) 1990-06-27 EP disclosed
US-4895837-A PARASITICIDES MERCK & CO., INC. (US) 1990-01-23 US disclosed