Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL28097100 | 1.00 | TSHR (0.60) | TSHRNAPRTTDP1TTRLMNA | |
| Pyridine SCHEMBL9703021 | 0.97 | — | — | |
| Pyridine SCHEMBL6517120 | 0.88 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL845238 | 0.88 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL3867441 | 0.88 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL27708567 | 0.88 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL8505767 | 0.88 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL1546704 | 0.85 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL3446743 | 0.85 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL22472321 | 0.85 | TSHR (0.50) | TSHRNAPRTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862807-B2 | Nanofibrous spongy microspheres | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-01-09 | — | — | US | claimed |
| CN-104672208-B | A kind of synthetic method of (3,5-bis trifluoromethyl pyrazolyl) pyridine derivate | 中国科学院大连化学物理研究所 | 2017-01-04 | — | — | CN | claimed |
| US-20160096941-A1 | NANOFIBROUS SPONGY MICROSPHERES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-04-07 | — | — | US | claimed |
| EP-0550875-B1 | Implantable polymeric device containing pharmaceutical agents and process for its production | SCHIERHOLZ JOERG DR DR (DE) | 1998-04-29 | — | — | EP | claimed |
| CN-113906057-B | Triblock copolymers and nanofiber gelling microspheres comprising same | 密歇根大学董事会 | 2023-10-20 | — | — | CN | disclosed |
| US-20220162398-A1 | TRI-BLOCK COPOLYMERS AND NANO-FIBROUS GELLING MICROSPHERES INCLUDING THE SAME | UNIV MICHIGAN REGENTS (US) | 2022-05-26 | — | — | US | disclosed |
| EP-3953400-A1 | TRI-BLOCK COPOLYMERS AND NANO-FIBROUS GELLING MICROSPHERES INCLUDING THE SAME | The Regents of The University of Michigan (US) | 2022-02-16 | — | — | EP | disclosed |
| CN-113906057-A | Triblock copolymer and nanofiber gelation microspheres comprising same | 密歇根大学董事会 | 2022-01-07 | — | — | CN | disclosed |
| US-11168077-B2 | Molecular rotor-based D-amino acids as tools for imaging peptidoglycan biosynthesis | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-20210047308-A1 | MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| WO-2020210533-A1 | TRI-BLOCK COPOLYMERS AND NANO-FIBROUS GELLING MICROSPHERES INCLUDING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-10-15 | — | — | WO | disclosed |
| US-4127658-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4100300-A | ANTIINFLAMMATORY, TRANQUILIZER | SANDOZ, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4032580-A | ANTI-INFLAMMATORY 1-PHENYL-2,3-BUTADIEN-1-OLS, METHODS OF USE AND COMPOSITIONS CONTAINING SAME | SANDOZ, INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-3997664-A | STEROIDS, ESTROGENIC, PROGESTATIONAL | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3969415-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3966736-A | 2,9-Dihydro-3H-pyrido[3,2-c]-s-triazolo[4,3-a][1,5]-benzodiazepin-3-ones | THE UPJOHN COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3961053-A | STEROIDS, CONTROLLING FERTILITY AND ESTRUS | SANDOZ, INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3931167-A | Process for the manufacture of 3-keto-6-azido-4,6-bis-dehydro-steroids and intermediates useful therein | SCHERING CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | TSHR 4198/4885NAPRT 1150/4885TDP1 1689/4885 |
| US-11168077-B2 | Molecular rotor-based D-amino acids as tools for imaging peptidoglycan biosynthesis | DDOST, DAD1, DAO | TSHR 3980/4885NAPRT 1562/4885TDP1 3316/4885 |
| US-20210047308-A1 | MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | DDOST, DAD1, DAO | TSHR 3980/4885NAPRT 1562/4885TDP1 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.