⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15776574 | 0.98 | — | — | |
| SCHEMBL12568357 | 0.77 | — | — | |
| SCHEMBL13282283 | 0.77 | — | — | |
| SCHEMBL3457913 | 0.77 | — | — | |
| SCHEMBL23133442 | 0.75 | TDP1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL19376296 | 0.75 | NAALAD2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL14157300 | 0.75 | NAALAD2 (0.39) | — | |
| SCHEMBL15131256 | 0.75 | CNR2 (0.31) | — | |
| SCHEMBL15998215 | 0.75 | MAPT (0.30) | — | |
| SCHEMBL806956 | 0.73 | DGAT1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102229-A1 | PYRROLYDINE DERIVATIVES AS IAP INHIBITORS | Novartis AG (CH) | 2009-09-23 | — | — | EP | claimed |
| WO-2008045905-A1 | PYRROLYDINE DERIVATIVES AS IAP INHIBITORS | NOVARTIS AG (CH) | 2008-04-17 | — | — | WO | claimed |
| US-20260027220-A1 | EPHA2 BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2026-01-29 | — | — | US | disclosed |
| US-20250381202-A1 | PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY | ZOUNEK ALEX (DE) | 2025-12-18 | — | — | US | disclosed |
| CN-107973791-B | Fused or tricyclic aryl pyrimidine compounds as kinase inhibitors | 南京圣和药业股份有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-107614503-B | Fused or tricyclic aryl pyrimidine compounds as kinase inhibitors | 广东众生药业股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| CN-107973791-A | Condensed ring or tricyclic Arylpyrimidines compound are used as kinase inhibitor | 南京圣和药业股份有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-104822266-B | Pesticidal compositions and methods related thereto | 陶氏益农公司 | 2017-12-05 | — | — | CN | disclosed |
| CN-104378986-B | Pesticidal compositions and methods related thereto | 陶氏益农公司 | 2017-05-31 | — | — | CN | disclosed |