Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.63 |
| ▸ | STS | P08842 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870562 | 1.00 | CA2 (0.63) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3869902 | 0.91 | CA2 (0.66) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3870735 | 0.91 | CA2 (0.65) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3866406 | 0.88 | ESR1 (0.54) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3872468 | 0.87 | CA2 (0.59) | CA2STSCA9KMT2ALMNA | |
| SCHEMBL3865630 | 0.86 | CA2 (0.66) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3868625 | 0.85 | CA2 (0.66) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3866395 | 0.84 | CA2 (0.77) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3868623 | 0.83 | CA2 (0.67) | CA2STSCA1CA9KMT2A | |
| SCHEMBL3871356 | 0.83 | CA2 (0.73) | CA2STSCA1CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534780-B2 | Estradiol prodrugs | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-05-19 | — | — | US | disclosed |