SCHEMBL9748569

SCHEMBL9748569

CCCCCC(Br)CCCCO[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.36
SLC28A2 O43868 1/20 0.36
SLC29A1 Q99808 1/20 0.36
SLC28A3 Q9HAS3 1/20 0.36
P2RY14 Q15391 1/20 0.34
P2RY6 Q15077 6/20 0.32
P2RY2 P41231 2/20 0.31
P2RY4 P51582 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3868098 0.92 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL18171337 0.91 SLC28A1 (0.36) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL861369 0.91 SLC28A1 (0.36) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL2732699 0.87 SLC28A1 (0.37) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL23673342 0.86 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL3885391 0.84 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL6919227 0.82 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4326832 0.82 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL1079788 0.82 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL17745010 0.81 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630650-B2 Engineered IgA antibodies and methods of use TIGATX, INC. (US) 2026-05-19 US disclosed
US-12285484-B2 Cancer associated antibody compositions and methods of use Absci Corporation (US) 2025-04-29 US disclosed
US-12258420-B2 Engineered IGA antibodies and methods of use TIGATX, INC. (US) 2025-03-25 US disclosed
US-20220204643-A1 CANCER ASSOCIATED ANTIBODY COMPOSITIONS AND METHODS OF USE Absci Corporation 2022-06-30 US disclosed
EP-3962953-A2 CANCER ASSOCIATED ANTIBODY COMPOSITIONS AND METHODS OF USE Target Discovery Merger Sub II, LLC (US) 2022-03-09 EP disclosed
EP-3947441-A1 ENGINEERED IGA ANTIBODIES AND METHODS OF USE UMC Utrecht Holding B.V. (NL) 2022-02-09 EP disclosed
US-20220031841-A1 CANCER ASSOCIATED ANTIBODY COMPOSITIONS AND METHODS OF USE Absci Corporation 2022-02-03 US disclosed
US-20210395395-A1 ENGINEERED IGA ANTIBODIES AND METHODS OF USE TIGA TX, INC. 2021-12-23 US disclosed
US-20210380720-A1 ENGINEERED IGA ANTIBODIES AND METHODS OF USE TIGA TX, INC. 2021-12-09 US disclosed
US-11091562-B2 Engineered IGA antibodies and methods of use UMC UTRECHT HOLDING B.V. (NL) 2021-08-17 US disclosed
EP-3853377-A1 CANCER ASSOCIATED ANTIBODY COMPOSITIONS AND METHODS OF USE Totient, Inc. (US) 2021-07-28 EP disclosed
US-11059909-B2 Engineered IgA antibodies and methods of use UMC UTRECHT HOLDING B.V. (NL) 2021-07-13 US disclosed
US-20210130462-A1 ENGINEERED IGA ANTIBODIES AND METHODS OF USE TIGA TX, INC. 2021-05-06 US disclosed
US-20210122834-A1 ENGINEERED IGA ANTIBODIES AND METHODS OF USE TIGA TX, INC. 2021-04-29 US disclosed
WO-2020223392-A2 CANCER ASSOCIATED ANTIBODY COMPOSITIONS AND METHODS OF USE TOTIENT, INC. (US) 2020-11-05 WO disclosed
WO-2020197400-A1 ENGINEERED IGA ANTIBODIES AND METHODS OF USE UMC UTRECHT HOLDING B.V. (NL) 2020-10-01 WO disclosed
WO-2020061337-A1 CANCER ASSOCIATED ANTIBODY COMPOSITIONS AND METHODS OF USE TOTIENT, INC. (US) 2020-03-26 WO disclosed
EP-0505566-A1 BIOSPECIFIC ANTIBODY TO CANCER CELL AND ENZYME WITH PRODRUG-ACTIVATING CHARACTERISTICS Takeda Chemical Industries, Ltd. (JP) 1992-09-30 EP disclosed
WO-1991009134-A1 BIOSPECIFIC ANTIBODY TO CANCER CELL AND ENZYME WITH PRODRUG-ACTIVATING CHARACTERISTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630650-B2 Engineered IgA antibodies and methods of use IGLV6-57, IGSF11, FCGR2A SLC28A1 728/4885SLC28A2 479/4885SLC29A1 1365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.