Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720999 | 1.00 | MIF (0.56) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL12463285 | 1.00 | MIF (0.56) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL4373785 | 0.79 | CYP2C19 (0.44) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL3814849 | 0.78 | KMT2A (0.62) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL4453575 | 0.78 | KMT2A (0.62) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL27465320 | 0.77 | MIF (0.56) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL1207891 | 0.77 | MIF (0.56) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL11392151 | 0.77 | MIF (0.56) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL11854703 | 0.77 | MIF (0.56) | MIFCYP2C19KMT2APKMPOLB | |
| SCHEMBL6778631 | 0.76 | ALDH1A1 (0.44) | CYP2C19KMT2APKMPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620910-B1 | Of given amino acid sequence; receptor agonists; increased metabolic stability; longer duration of action; use in treatment of non-insulin-dependent type II diabetes, obesity, and type I diabetes | LES LABORATOIRES SERVIER (FR) | 2003-09-16 | — | — | US | claimed |
| CN-1232038-A | New peptide compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-10-20 | — | — | CN | claimed |
| EP-2978772-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978771-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014161781-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014161782-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| EP-2100875-A1 | Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives | Takasago International Corporation (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-20090124654-A1 | Aryl and Heteroaryl Compounds, Compositions, Methods of Use | TRANSTECH PHARMA, INC. | 2009-05-14 | — | — | US | disclosed |
| EP-1888566-A1 | 2-[(ISOQUINOLIN-3-CARBONYL)AMINO]-PROPIONIC ACID DERIVATIVES AS INHIBITORS OF FACTORS XI AND IX FOR THE TREATMENT OF THROMBOSIS | Transtech Pharma, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20070254916-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | MJALLI ADNAN M | 2007-11-01 | — | — | US | disclosed |
| US-7262269-B2 | Method for screening combinational bead library; ligands for cancer cells | THE REGENTS OF UNIVERSITY OF CALIFORNIA (US) | 2007-08-28 | — | — | US | disclosed |
| EP-1646718-A2 | METHODS FOR THE STEREOSELECTIVE SYNTHESIS AND ENANTIOMERIC ENRICHMENT OF B-AMINO ACIDS | Pharmacia Corporation (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1621529-A1 | 3-AMINO-3-ARYLPROPIONIC ACID n-ALKYL ESTERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-3-ARYLPROPIONIC ACIDS AND ESTERS OF THE ANTIPODES THERETO | Ube Industries, Ltd. (JP) | 2006-02-01 | — | — | EP | disclosed |
| US-20050171148-A1 | Aryl and heteroaryl compounds, compositions, methods of use | TRANSTECH PHARMA, LLC | 2005-08-04 | — | — | US | disclosed |
| WO-2005045430-A1 | SCREENING COMBINATORIAL BEAD LIBRARIES FOR CANCER LIGANDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2005005633-A2 | METHODS FOR THE STEREOSELECTIVE SYNTHESIS AND ENANTIOMERIC ENRICHMENT OF B-AMINO ACIDS | PHARMACIA CORPORATION (US) | 2005-01-20 | — | — | WO | disclosed |
| US-20050009151-A1 | Methods for the stereospecific and enantiomeric enrichment of beta-amino acids | PHARMACIA CORPORATION | 2005-01-13 | — | — | US | disclosed |
| US-20040096906-A1 | Method for screening combinatorial bead library; ligands for cancer cells | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-20 | — | — | US | disclosed |
| US-6620910-B1 | Of given amino acid sequence; receptor agonists; increased metabolic stability; longer duration of action; use in treatment of non-insulin-dependent type II diabetes, obesity, and type I diabetes | LES LABORATOIRES SERVIER (FR) | 2003-09-16 | — | — | US | disclosed |
| CN-1232038-A | New peptide compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-10-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096906-A1 | Method for screening combinatorial bead library; ligands for cancer cells | EPCAM, MKI67, FGFR3 | MIF 252/4885CYP2C19 4805/4885KMT2A 2986/4885 |
| US-20090124654-A1 | Aryl and Heteroaryl Compounds, Compositions, Methods of Use | F3, F12, CFH | MIF 3828/4885CYP2C19 103/4885KMT2A 1874/4885 |
| US-20070254916-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | TFPI, F9, F3 | MIF 3870/4885CYP2C19 35/4885KMT2A 1257/4885 |
| US-20050171148-A1 | Aryl and heteroaryl compounds, compositions, methods of use | TFPI, F3, F2 | MIF 3631/4885CYP2C19 46/4885KMT2A 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.