Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 14/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 13/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481437 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28333963 | 0.95 | KDM4E (0.39) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| Iodide SCHEMBL8863463 | 0.95 | KDM4E (0.42) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| Formamide SCHEMBL28309029 | 0.88 | KDM4E (0.38) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL28336484 | 0.80 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL28003674 | 0.77 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL2263114 | 0.75 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| Hydrochloric Acid SCHEMBL28992847 | 0.75 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| Bromide SCHEMBL29573873 | 0.74 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| Bromide SCHEMBL636878 | 0.74 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064068-A1 | INK-JET RECORDING METHOD, INK-JET RECORDING APPARATUS AND RECORDED MATTER | Ricoh Company, Ltd. (JP) | 2009-06-03 | — | — | EP | disclosed |
| WO-2009001967-A1 | INK-JET RECORDING METHOD, INK-JET RECORDING APPARATUS AND RECORDED MATTER | RICOH COMPANY, LTD. (JP) | 2008-12-31 | — | — | WO | disclosed |