Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 8/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC19A2 | O60779 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29573873 | 1.00 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL29822577 | 0.98 | — | — | |
| SCHEMBL627705 | 0.98 | — | — | |
| Bromide SCHEMBL28752556 | 0.96 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| Hydrochloric Acid SCHEMBL338519 | 0.95 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| Iodide SCHEMBL4316516 | 0.95 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| Fluoride Ion SCHEMBL9326053 | 0.95 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| Bromide SCHEMBL28752555 | 0.93 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL30330753 | 0.91 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL8505609 | 0.89 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | UNIV MURCIA (ES) | 2026-03-19 | — | — | US | claimed |
| EP-4556514-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | Universidad de Murcia (ES) | 2025-05-21 | — | — | EP | claimed |
| CN-114566723-B | Electrolyte for rechargeable electrochemical cells | EOS能源技术控股有限责任公司 | 2025-03-04 | — | — | CN | claimed |
| CN-114007703-B | Quaternary ammonium halides for treating halogen pollution | 溴化合物有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-4315482-A1 | HALOGEN COMPLEXING AGENTS BOUND TO THE CATHODE SURFACE IN A STATIC ZINC HALIDE BATTERY | EOS Energy Technology Holdings, LLC (US) | 2024-02-07 | — | — | EP | claimed |
| EP-3204977-B1 | ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL | EOS ENERGY TECH HOLDINGS LLC (US) | 2023-12-20 | — | — | EP | claimed |
| US-20220320514-A1 | HALOGEN COMPLEXING AGENTS BOUND TO THE CATHODE SURFACE IN A STATIC ZINC HALIDE BATTERY | EOS ENERGY STORAGE LLC (US) | 2022-10-06 | — | — | US | claimed |
| WO-2022212163-A1 | HALOGEN COMPLEXING AGENTS BOUND TO THE CATHODE SURFACE IN A STATIC ZINC HALIDE BATTERY | EOS ENERGY STORAGE LLC (US) | 2022-10-06 | — | — | WO | claimed |
| CN-114566723-A | Electrolyte for rechargeable electrochemical cells | EOS能源储存有限责任公司 | 2022-05-31 | — | — | CN | claimed |
| CN-114007703-A | Quaternary ammonium halides for treatment of halogen contamination | 溴化合物有限公司 | 2022-02-01 | — | — | CN | claimed |
| US-20140262818-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | BROMINE COMPOUNDS LTD. (IL) | 2014-09-18 | — | — | US | claimed |
| WO-2014122641-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | BROMINE COMPOUNDS LTD. (IL) | 2014-08-14 | — | — | WO | claimed |
| EP-2758373-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | Bromine Compounds Ltd. (IL) | 2014-07-30 | — | — | EP | claimed |
| EP-2759016-A1 | ADDITIVES FOR HYDROGEN/ BROMINE CELLS | Bromine Compounds Ltd. (IL) | 2014-07-30 | — | — | EP | claimed |
| WO-2013168145-A1 | ADDITIVES FOR ZINC-BROMINE MEMBRANELESS FLOW CELLS | BROMINE COMPOUNDS LTD. (IL) | 2013-11-14 | — | — | WO | claimed |
| WO-2013042110-A1 | ADDITIVES FOR HYDROGEN/ BROMINE CELLS | BROMINE COMPOUNDS LTD. (IL) | 2013-03-28 | — | — | WO | claimed |
| WO-2013042109-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | BROMINE COMPOUNDS LTD. (IL) | 2013-03-28 | — | — | WO | claimed |
| EP-1006374-B1 | Process for producing a resin having a large refractive index | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-01-07 | — | — | EP | claimed |
| US-5607815-A | CONTAINING ARYLHYDRAZIDE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | claimed |
| US-5384232-A | Process for rapid access development of silver halide films using pyridinium as development accelerators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140262818-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | MEP1B, MEP1A, EDNRB | ACHE 372/4885NPC1 3849/4885RAB9A 2466/4885 |
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | FGB, POLR2B, POLB | ACHE 3626/4885NPC1 4769/4885RAB9A 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.