Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | ATF4 | P18848 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870324 | 1.00 | KMT2A (0.51) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3869586 | 0.84 | ATF4 (0.66) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3869587 | 0.84 | ATF4 (0.66) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL13853081 | 0.83 | MEN1 (0.57) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3871504 | 0.83 | MEN1 (0.57) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3869202 | 0.82 | MEN1 (0.59) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3869200 | 0.82 | MEN1 (0.59) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3870001 | 0.81 | NPC1 (0.48) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3869999 | 0.81 | NPC1 (0.48) | KMT2AMEN1CXCR6LTA4HMAPT | |
| SCHEMBL3873444 | 0.80 | NPC1 (0.53) | KMT2AMEN1CXCR6LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891064-B1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | ALMIRALL SA (ES) | 2009-09-02 | — | — | EP | claimed |