Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956603 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6039088 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL28329896 | 0.84 | MEN1 (0.50) | KDM4ELMNADHODHPKML3MBTL1 | |
| SCHEMBL10985872 | 0.81 | ELANE (0.51) | KDM4EALDH1A1LMNAGLADHODH | |
| SCHEMBL11839555 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL808420 | 0.79 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL30716830 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL17829222 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3337344 | 0.76 | PARP1 (0.44) | ELANEPARP1TDP1 | |
| SCHEMBL30013654 | 0.76 | PARP1 (0.44) | ELANEPARP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100507-A1 | SUBSTANCE CAPABLE OF INHIBITING CYTOKININ SIGNALING | Sumitomo Chemical Company, Limited (JP) | 2009-09-16 | — | — | EP | disclosed |