Sugi Predict

Sugi Predict / Compounds / SCHEMBL808420

SCHEMBL808420

SCHEMBL808420

Clc1nc(-c2ccccc2)c2ccccc2n1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 8/20 0.77
▸ ALDH1A1 P00352 7/20 0.77
▸ LMNA P02545 5/20 0.64
▸ MAPT P10636 4/20 0.64
▸ HPGD P15428 4/20 0.61
▸ GLA P06280 2/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ NUDT1 P36639 3/20 0.60
▸ ADORA2A P29274 2/20 0.60
▸ KMT2A Q03164 4/20 0.55
▸ OPRK1 P41145 1/20 0.55
▸ MEN1 O00255 3/20 0.55
▸ GAA P10253 3/20 0.55
▸ PKM P14618 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ L3MBTL1 Q9Y468 3/20 0.52
▸ HTT P42858 1/20 0.52
▸ ATM Q13315 1/20 0.51
▸ RAD52 P43351 1/20 0.50
▸ MAOA P21397 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL808191 0.96 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL17286874 0.96 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTHPGD
Hydrochloric Acid SCHEMBL5803147 0.96 KDM4E (0.72) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL5803149 0.94 KDM4E (0.70) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL4087331 0.90 KDM4E (0.75) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL17299607 0.89 KDM4E (0.69) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL20258996 0.89 ALDH1A1 (0.68) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL15810834 0.89 ALDH1A1 (0.63) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL17299602 0.88 KDM4E (0.67) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL22607015 0.87 KDM4E (0.71) KDM4EALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109485610-B Method for synthesizing 2-chloro-4-phenylquinazoline by one-pot method 安徽秀朗新材料科技有限公司 2020-07-24 — — CN claimed
CN-109485610-A The method of the chloro- 4- phenylquinazoline of one pot process 2- 安徽秀朗新材料科技有限公司 2019-03-19 — — CN claimed
CN-105198806-B A kind of method using aromatic amine, diketone synthesis of quinoline derivatives 南阳师范学院 2017-11-21 — — CN claimed
CN-107082765-A A kind of synthetic method of the phenylquinazoline of 2 chlorine 4 常州大学 2017-08-22 — — CN claimed
CN-106892925-A A kind of OLED material based on pyrrolo carbazole derivatives and preparation method thereof 西安瑞联新材料股份有限公司 2017-06-27 — — CN claimed
EP-0536360-A4 TOPICAL TREATMENT OF ACNE — 1993-08-04 — — EP claimed
EP-0536360-A1 TOPICAL TREATMENT OF ACNE BLOOM, Leonard (US) 1993-04-14 — — EP claimed
WO-1992015299-A1 TOPICAL TREATMENT OF ACNE BLOOM, LEONARD (US) 1992-09-17 — — WO claimed
JP-56092875-A — — None — — JP disclosed
US-12637466-B2 Benzocarbazole-based compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2026-05-26 — — US disclosed
CN-114763349-B Organic compound, application and preparation method thereof and organic electroluminescent device using same 北京鼎材科技股份有限公司 2026-05-22 — — CN disclosed
US-20260082809-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO LTD (KR) 2026-03-19 — — US disclosed
US-12459946-B2 Organic host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2025-11-04 — — US disclosed
US-12415949-B2 Compound, organic electroluminescent device, and display device SK INC. (KR) 2025-09-16 — — US disclosed
WO-1992015299-A1 TOPICAL TREATMENT OF ACNE BLOOM, LEONARD (US) 1992-09-17 — — WO disclosed
WO-1992001675-A2 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS RHONE-POULENC RORER S.A. (FR) 1992-02-06 — — WO disclosed
US-5011997-A Process for bis(4-aminophenyl)hexafluoropropane HOECHST CELANESE CORP. (US) 1991-04-30 — — US disclosed
US-4906741-A Azo dimers containing the hexafluoroisopropylidene group HOECHST CELANESE CORPORATION (US) 1990-03-06 — — US disclosed
EP-0311028-A2 A process for bis (4-aminophenyl) hexafluoropropane HOECHST CELANESE CORPORATION (US) 1989-04-12 — — EP disclosed
JP-S5692875-A 2-AMINOQUINAZOLINE DERIVATIVE DAINIPPON PHARMACEUT CO LTD 1981-07-27 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415949-B2 Compound, organic electroluminescent device, and display device L1CAM, EML4, OCIAD2 KDM4E 3234/4885ALDH1A1 184/4885LMNA 1645/4885
US-12459946-B2 Organic host materials for electroluminescent devices RPS4X, RPS4Y1, MRPS34 KDM4E 954/4885ALDH1A1 2022/4885LMNA 2768/4885
US-12637466-B2 Benzocarbazole-based compound and organic light-emitting device comprising same CYP1A1, CYP2E1, CYP3A4 KDM4E 1432/4885ALDH1A1 341/4885LMNA 549/4885
US-20260082809-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER CRY1, CRY2, CYC1 KDM4E 3952/4885ALDH1A1 1460/4885LMNA 908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.