Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL3867785 | 0.96 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4AKR1B1 | |
| Succinic Acid SCHEMBL1046259 | 0.92 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Succinic Acid SCHEMBL3870450 | 0.92 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL11649333 | 0.88 | FFAR3 (0.52) | TSHRHPGDALDH1A1CYP3A4AKR1B1 | |
| Acrylic Acid Ethyl Ester SCHEMBL6009066 | 0.87 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL21715365 | 0.85 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL29739797 | 0.85 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL9557413 | 0.85 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL3180 | 0.85 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL8159679 | 0.85 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809688-A1 | LASER ENGRAVEABLE COMPOSITIONS FOR RELIEF IMAGE PRINTING ELEMENTS | NAPP SYSTEMS, INC. (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013116011-A1 | LASER ENGRAVEABLE COMPOSITIONS FOR RELIEF IMAGE PRINTING ELEMENTS | NAPP SYSTEMS, INC. (US) | 2013-08-08 | — | — | WO | disclosed |
| US-20130196144-A1 | Laser Engraveable Compositions for Relief Image Printing Elements | NAPP SYSTEMS, INC. | 2013-08-01 | — | — | US | disclosed |
| US-7625959-B2 | Curable jettable liquid for flexography | AGFA GRAPHICS, N.V. (BE) | 2009-12-01 | — | — | US | disclosed |
| EP-1637322-B1 | Method for manufacturing a flexographic printing master | AGFA GRAPHICS NV (BE) | 2009-05-13 | — | — | EP | disclosed |
| EP-1637926-B1 | Curable jettable liquid for the production of a flexographic printing plate | AGFA GRAPHICS NV (BE) | 2009-04-22 | — | — | EP | disclosed |
| US-7401552-B2 | Method for manufacturing a flexographic printing master | AGFA GRAPHICS N.V. (BE) | 2008-07-22 | — | — | US | disclosed |
| US-20060073417-A1 | Photopolymer plate and method for imaging the surface of a photopolymer plate | HERMESDORF MARK | 2006-04-06 | — | — | US | disclosed |
| EP-1637926-A2 | Curable jettable liquid for the production of a flexographic printing plate | Agfa-Gevaert (BE) | 2006-03-22 | — | — | EP | disclosed |
| EP-1637322-A2 | Method for manufacturing a flexographic printing master | Agfa-Gevaert (BE) | 2006-03-22 | — | — | EP | disclosed |
| US-5021321-A | Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator | CANON KABUSHIKI KAISHA (JP) | 1991-06-04 | — | — | US | disclosed |
| US-5001032-A | Photosensitive material containing a photosensitive and heat developable element and a polymerizable layer and image-forming method utilizing the same | CANON KABUSHIKI KAISHA (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0412851-A2 | Photosensitive member and multi-color image forming method | CANON KABUSHIKI KAISHA (JP) | 1991-02-13 | — | — | EP | disclosed |
| EP-0410803-A2 | Image forming device | CANON KABUSHIKI KAISHA (JP) | 1991-01-30 | — | — | EP | disclosed |
| EP-0363790-A2 | Image forming method and image forming medium | CANON KABUSHIKI KAISHA (JP) | 1990-04-18 | — | — | EP | disclosed |
| EP-0362827-A1 | Image forming method and image forming medium | CANON KABUSHIKI KAISHA (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0360014-A1 | Photosensitive material and image forming method using same | CANON KABUSHIKI KAISHA (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0332455-A2 | Photosensitive material and image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0328364-A2 | Photosensitive material | CANON KABUSHIKI KAISHA (JP) | 1989-08-16 | — | — | EP | disclosed |
| EP-0326424-A2 | Photosensitive composition, photosensitive material, and image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-08-02 | — | — | EP | disclosed |