SCHEMBL3871771

SCHEMBL3871771

Nc1ccc2c(C(=O)O)c(O)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
CYP2C19 P33261 3/20 0.52
HSD17B10 Q99714 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
HPGD P15428 2/20 0.52
THRB P10828 2/20 0.52
RECQL P46063 2/20 0.52
CYP2C9 P11712 2/20 0.52
ALOX15 P16050 2/20 0.52
TNF P01375 1/20 0.52
HSPD1 P10809 1/20 0.52
CASP1 P29466 1/20 0.52
PTGS2 P35354 1/20 0.52
KDR P35968 1/20 0.52
BRCA1 P38398 1/20 0.52
CASP7 P55210 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10950376 0.86 PLAU (0.50) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL28344679 0.84 KMT2A (0.48) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL5636668 0.83 KDM4E (0.50) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL21612710 0.82 ALDH1A1 (0.52) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL30178354 0.81 CA12 (0.48) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL732139 0.81 CA12 (0.48) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL2747254 0.81 ALDH1A1 (0.43) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL13573125 0.81 CA1 (0.50) KDM4EALDH1A1CYP3A4MEN1KMT2A
SCHEMBL3914003 0.80 KDM4E (0.53) KDM4EALDH1A1MEN1KMT2ACYP2C19
SCHEMBL29678802 0.79 ALDH1A1 (0.44) KDM4EALDH1A1MEN1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754756-B1 Carbon material ORION ENG CARBONS GMBH (DE) 2016-12-07 EP disclosed
EP-2130880-A1 ink jet ink Evonik Degussa GmbH (DE) 2009-12-09 EP disclosed
EP-1754756-A2 Carbon material Degussa AG (DE) 2007-02-21 EP disclosed
US-20070031319-A1 Carbon material DEGUSSA AG (DE) 2007-02-08 US disclosed