Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991523 | 0.87 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9140957 | 0.87 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13645967 | 0.85 | MEN1 (0.68) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10341056 | 0.80 | CHRM2 (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10340918 | 0.80 | CHRM2 (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10340997 | 0.80 | CHRM2 (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10340852 | 0.80 | CHRM2 (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10340824 | 0.80 | CHRM2 (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10341018 | 0.80 | CHRM2 (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10340818 | 0.80 | CHRM2 (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601180-B2 | Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | claimed |
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'OREAL S.A. (FR) | 2009-02-26 | — | — | US | claimed |
| US-7601180-B2 | Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'OREAL S.A. (FR) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | KRT18, S100A4, S100P | MEN1 2692/4885KMT2A 1544/4885MAPT 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.