Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877791 | 0.89 | — | — | |
| SCHEMBL3869743 | 0.87 | — | — | |
| SCHEMBL3869794 | 0.85 | MEN1 (0.37) | SMN1; SMN2PKM | |
| SCHEMBL3869123 | 0.79 | ALDH1A1 (0.33) | SMN1; SMN2PKM | |
| SCHEMBL3875283 | 0.77 | CHRM2 (0.33) | DRD2SMN1; SMN2 | |
| SCHEMBL10725768 | 0.76 | STAT3 (0.35) | SMN1; SMN2 | |
| SCHEMBL3870644 | 0.75 | ALDH1A1 (0.31) | SMN1; SMN2PKM | |
| SCHEMBL4707472 | 0.74 | MEN1 (0.31) | — | |
| SCHEMBL4706994 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL1345075 | 0.73 | ALDH1A1 (0.40) | DRD2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013182-A2 | AMINOQUINOLONES AS GSK-3 INHIBITORS | Activx Biosciences, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007106537-A2 | AMINOQUINOLONES AS GSK-3 INHIBITORS | ACTIVX BIOSCIENCES, INC. (US) | 2007-09-20 | — | — | WO | disclosed |