Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 18/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883346 | 0.85 | SSTR5 (0.55) | SSTR5KCNH2SSTR3KDM4EALDH1A1 | |
| SCHEMBL3872726 | 0.84 | SSTR5 (0.44) | SSTR5KCNH2SSTR3KDM4EALDH1A1 | |
| SCHEMBL3873987 | 0.83 | SSTR5 (0.68) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3871205 | 0.81 | SSTR5 (0.47) | SSTR5KCNH2SSTR3KDM4EALDH1A1 | |
| SCHEMBL1875443 | 0.81 | ALDH1A1 (0.47) | SSTR5KCNH2SSTR3KDM4EALDH1A1 | |
| SCHEMBL3871844 | 0.81 | SSTR5 (0.56) | SSTR5KDM4EALDH1A1TSHR | |
| SCHEMBL3876136 | 0.80 | SSTR5 (0.58) | SSTR5KCNH2SSTR3 | |
| SCHEMBL29087391 | 0.80 | KDM4E (0.68) | SSTR5KDM4EALDH1A1TSHR | |
| SCHEMBL1748416 | 0.80 | ALDH1A1 (0.58) | SSTR5KDM4EALDH1A1 | |
| SCHEMBL1748320 | 0.80 | SSTR5 (0.55) | SSTR5KCNH2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-B1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-10-14 | — | — | EP | disclosed |