SCHEMBL3872618

SCHEMBL3872618

C#CC(N)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919845 1.00
SCHEMBL6777081 1.00
Hydrochloric Acid SCHEMBL18049977 0.97
Hydrochloric Acid SCHEMBL7503559 0.97
Hydrochloric Acid SCHEMBL6773521 0.97
Trifluoroacetic Acid SCHEMBL17822815 0.87 LMNA (0.48)
SCHEMBL27348021 0.80 CYP2D6 (0.42)
SCHEMBL25383152 0.79
SCHEMBL25383149 0.79
Hydrochloric Acid SCHEMBL25381571 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101525299-B Method for synthesizing beta-amino acid ASTATECH CHENGDU PHARMACEUTICAL CO LTD 2013-11-20 CN claimed
EP-0839128-B1 PROCESS FOR THE PREPARATION OF ETHYL 3S-[[4-[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]-1,4-DIOXOBUTYL]AMINO]-4-PENTYNOATE SEARLE & CO (US) 2000-04-05 EP claimed
EP-0839128-A1 PROCESS FOR THE PREPARATION OF ETHYL 3S-[[4-[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]-1,4-DIOXOBUTYL]AMINO]-4-PENTYNOATE G.D. SEARLE &amp; CO. (US) 1998-05-06 EP claimed
US-5631399-A MULTISTAGE SYNTHESIS USING TRIMETHYLSILYLACETYLENE WITH BUTYLLITHIUM AND FORMYLMORPHOLINE, THEN ACID HYDROLYSIS G. D. SEARLE & CO. (US) 1997-05-20 US claimed
WO-1997003947-A1 PROCESS FOR THE PREPARATION OF ETHYL 3S-[[4-[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]-1,4-DIOXOBUTYL]AMINO]-4-PENTYNOATE G.D. SEARLE & CO. (US) 1997-02-06 WO claimed
US-5536869-A Process for the preparation of ethyl 3S-[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino]-4-pentynoate G. D. SEARLE & CO. (US) 1996-07-16 US claimed
CN-101525299-B Method for synthesizing beta-amino acid ASTATECH CHENGDU PHARMACEUTICAL CO LTD 2013-11-20 CN disclosed
CN-101525299-A Method for synthesizing beta-amino acid ASTATECH CHENGDU PHARMACEUTICA 2009-09-09 CN disclosed
EP-1047425-A4 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 2009-04-22 EP disclosed
EP-1427840-B1 ENZYMATIC METHOD FOR THE ENANTIOMERIC RESOLUTION OF AMINO ACIDS AVENTIS PHARMA SA (FR) 2006-10-04 EP disclosed
EP-1044001-B1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 2005-07-06 EP disclosed
EP-1040111-B1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 2005-06-22 EP disclosed
EP-1040098-B1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 2005-04-27 EP disclosed
US-5536869-A Process for the preparation of ethyl 3S-[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino]-4-pentynoate G. D. SEARLE & CO. (US) 1996-07-16 US disclosed
WO-1995008536-A1 N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-03-30 WO disclosed
EP-0614360-A1 SUBSTITUTED -g(b)-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. SEARLE & CO (US) 1994-09-14 EP disclosed
US-5344957-A Amidinoiphenyl-substituted G.D. SEARLE & CO. (US) 1994-09-06 US disclosed
EP-0542708-A1 Substituted B-amino acid derivatives useful as platelet aggregation inhibitors MONSANTO COMPANY (US) 1993-05-19 EP disclosed
WO-1993007867-A1 SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1993-04-29 WO disclosed
US-4582529-A PRE-AND POST- EMERGENCE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY 1986-04-15 US disclosed