Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873431 | 0.97 | MAPT (0.47) | MAPTKDM4EATMTAAR1ACHE | |
| SCHEMBL3873017 | 0.97 | MAPT (0.47) | MAPTKDM4EATMTAAR1ACHE | |
| SCHEMBL2954181 | 0.84 | TAAR1 (0.56) | MAPTKDM4EATMTAAR1ACHE | |
| SCHEMBL12363876 | 0.82 | MAPT (0.39) | MAPTKDM4EATMTAAR1ACHE | |
| SCHEMBL12330214 | 0.81 | TAAR1 (0.48) | MAPTKDM4EATMTAAR1ACHE | |
| SCHEMBL1711296 | 0.81 | CYP3A4 (0.53) | MAPTKDM4EACHENQO2PDE3B | |
| SCHEMBL29368836 | 0.81 | CYP3A4 (0.53) | MAPTKDM4EACHENQO2PDE3B | |
| SCHEMBL12593193 | 0.79 | KDM4E (0.46) | MAPTKDM4EATMTAAR1MEN1 | |
| SCHEMBL12593179 | 0.79 | HDAC3 (0.42) | MAPTKDM4EATMTAAR1CYP19A1 | |
| SCHEMBL8269049 | 0.79 | TAAR1 (0.52) | MAPTKDM4EATMTAAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585928-B2 | monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices | DOW GLOBAL TECHNOLOGIES (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2007-02-01 | — | — | US | disclosed |
| WO-2005042613-A1 | MULTIFUNCTIONAL MONOMERS CONTAINING BOUND MESOGENIC PORAGEN FORMING MOIETIES AND POLYARYLENE COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | LRBA, CD74, BMP2 | MAPT 4021/4885KDM4E 4789/4885ATM 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.