Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 3/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220902 | 0.87 | F10 (0.66) | F10TP53ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL3873911 | 0.81 | F10 (0.72) | F10 | |
| SCHEMBL3875763 | 0.80 | F10 (0.47) | F10TP53 | |
| SCHEMBL3875017 | 0.79 | F10 (0.49) | F10TP53 | |
| SCHEMBL3879157 | 0.78 | F10 (0.46) | F10TP53 | |
| SCHEMBL3873832 | 0.76 | F10 (0.65) | F10 | |
| SCHEMBL3872859 | 0.75 | F10 (0.58) | F10 | |
| SCHEMBL3874943 | 0.74 | F10 (0.43) | F10ALDH1A1 | |
| SCHEMBL3876204 | 0.73 | F10 (0.42) | F10 | |
| SCHEMBL3872604 | 0.72 | F10 (0.42) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | claimed |