⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453306 | 0.94 | — | — | |
| SCHEMBL1041966 | 0.94 | — | — | |
| SCHEMBL3253204 | 0.93 | — | — | |
| SCHEMBL1042876 | 0.87 | DRD2 (0.34) | — | |
| SCHEMBL1078366 | 0.87 | DRD2 (0.31) | — | |
| SCHEMBL1041974 | 0.86 | — | — | |
| SCHEMBL1043800 | 0.84 | PIK3CA (0.30) | — | |
| SCHEMBL1043799 | 0.84 | PIK3CA (0.30) | — | |
| SCHEMBL29453343 | 0.84 | PIK3CA (0.30) | — | |
| SCHEMBL1043933 | 0.84 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1872159-B1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS WITH REACTIVE SUBSTITUENTS | JOHNSON AND JOHNSON VISION CARE INC (US) | 2019-09-04 | — | — | EP | claimed |
| US-9052438-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-06-09 | — | — | US | claimed |
| EP-3331581-B1 | MECHANOPHORIC MEDICAL PRODUKT | AESCULAP AG (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-9052438-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-7556750-B2 | Photochromic materials with reactive substituents | TRANSITIONS OPTICAL, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20060226401-A1 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. | 2006-10-12 | — | — | US | disclosed |