SCHEMBL3873329

SCHEMBL3873329

C=C(C)C(=O)CCOC(=O)c1ccccc1C(=O)OCCC(=O)C(=C)C

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.58
TSHR P16473 9/20 0.56
TDP1 Q9NUW8 4/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
CYP3A4 P08684 4/20 0.53
MAPK1 P28482 3/20 0.53
TP53 P04637 2/20 0.53
LMNA P02545 1/20 0.51
NPC1 O15118 2/20 0.47
HSD17B10 Q99714 4/20 0.44
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
PTGS2 P35354 1/20 0.42
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30414145 0.94 ALDH1A1 (0.51) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL3873330 0.94 ALDH1A1 (0.51) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL2342289 0.90 TSHR (0.60) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL28770367 0.89 TSHR (0.61) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL28716635 0.86 ALDH1A1 (0.61) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL24199837 0.82 TSHR (0.49) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL11202741 0.81 TSHR (0.41) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL129437 0.81 TSHR (0.62) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL30901583 0.81 ALDH1A1 (0.59) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL29220215 0.81 ALDH1A1 (0.59) ALDH1A1TSHRTDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7625959-B2 Curable jettable liquid for flexography AGFA GRAPHICS, N.V. (BE) 2009-12-01 US claimed
EP-1637926-B1 Curable jettable liquid for the production of a flexographic printing plate AGFA GRAPHICS NV (BE) 2009-04-22 EP claimed
EP-1637926-A2 Curable jettable liquid for the production of a flexographic printing plate Agfa-Gevaert (BE) 2006-03-22 EP claimed
US-20060054040-A1 Curable jettable liquid for flexography AGFA-GEVAERT (BE) 2006-03-16 US claimed
CN-111650811-A White photosensitive film and preparation method and application thereof 上海孚赛特新材料股份有限公司 2020-09-11 CN disclosed
US-7625959-B2 Curable jettable liquid for flexography AGFA GRAPHICS, N.V. (BE) 2009-12-01 US disclosed
EP-1637322-B1 Method for manufacturing a flexographic printing master AGFA GRAPHICS NV (BE) 2009-05-13 EP disclosed
EP-1637926-B1 Curable jettable liquid for the production of a flexographic printing plate AGFA GRAPHICS NV (BE) 2009-04-22 EP disclosed
US-7401552-B2 Method for manufacturing a flexographic printing master AGFA GRAPHICS N.V. (BE) 2008-07-22 US disclosed
EP-1637926-A2 Curable jettable liquid for the production of a flexographic printing plate Agfa-Gevaert (BE) 2006-03-22 EP disclosed
EP-1637322-A2 Method for manufacturing a flexographic printing master Agfa-Gevaert (BE) 2006-03-22 EP disclosed
US-20060055761-A1 Method for manufacturing a flexographic printing master AGFA-GEVAERT (BE) 2006-03-16 US disclosed
US-20060054040-A1 Curable jettable liquid for flexography AGFA-GEVAERT (BE) 2006-03-16 US disclosed
US-4579904-A DENTAL RESTORATIVES AND PILLING MATERIALS BLENDAX WERKE R. SCHNEIDER GMBH & CO. (DE) 1986-04-01 US disclosed
EP-0044352-B1 ADDUCTS FROM DIISOCYANATES AND METHACRYLOYLALKYLETHERS, -ALCOXYBENZENES RESP. -ALCOXYCYCLOALCANES AND THEIR USE Blendax-Werke R. Schneider GmbH & Co. (DE) 1985-02-20 EP disclosed
US-4420306-A DENTAL RESTORATIVE AND FILLING MATERIAL BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) 1983-12-13 US disclosed
US-4383826-A DICARBAMATE COMPOUNDS USED FOR MAKING PROSTHETIC TEETH BLENDAX-WERKE R.SCHNEIDER GMBH & CO. (DE) 1983-05-17 US disclosed