Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.60 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873620 | 0.84 | P2RX3 (0.64) | P2RX3TGFBR1MEN1KMT2ATSHR | |
| SCHEMBL1307191 | 0.83 | P2RX3 (0.66) | P2RX3TGFBR1MEN1KMT2ATSHR | |
| SCHEMBL3852223 | 0.80 | P2RX3 (0.55) | P2RX3TGFBR1ALDH1A1KDM4EADAMTS4 | |
| SCHEMBL1307193 | 0.79 | P2RX3 (0.67) | P2RX3TGFBR1MEN1KMT2ATSHR | |
| SCHEMBL1305720 | 0.78 | P2RX3 (0.70) | P2RX3TGFBR1MEN1KMT2ATSHR | |
| SCHEMBL1305459 | 0.78 | P2RX3 (0.60) | P2RX3TGFBR1 | |
| SCHEMBL1307315 | 0.78 | P2RX3 (0.66) | P2RX3TGFBR1MEN1KMT2ATSHR | |
| SCHEMBL1307318 | 0.78 | P2RX3 (0.66) | P2RX3TGFBR1MEN1KMT2ATSHR | |
| SCHEMBL3817692 | 0.78 | P2RX3 (0.67) | P2RX3TGFBR1MEN1KMT2ATSHR | |
| SCHEMBL1307194 | 0.77 | P2RX3 (0.67) | P2RX3TGFBR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |