Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | APAF1 | O14727 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.58 |
| ▸ | ITGAL | P20701 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873868 | 1.00 | KDM4E (0.61) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL170877 | 0.88 | KDM4E (0.69) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL170878 | 0.88 | KDM4E (0.69) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL991035 | 0.87 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL991039 | 0.87 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| Water SCHEMBL5384989 | 0.87 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| Water SCHEMBL5384991 | 0.87 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL7855506 | 0.85 | SMN1; SMN2 (0.74) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL4987528 | 0.83 | SMN1; SMN2 (0.76) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL13762546 | 0.82 | KDM4E (0.77) | KDM4EMAPTAPAF1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999256-A4 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORP (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1999256-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Verenium Corporation (US) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007103989-A9 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORP (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007103989-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION (US) | 2007-09-13 | — | — | WO | disclosed |