SCHEMBL38740

SCHEMBL38740

C=CC(N)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
HTR2A P28223 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1534125 1.00 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1683556 1.00 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL253354 0.97 DPP4 (0.48) DPP4F2HTR2ATAAR1ADRA2A
Hydrochloric Acid SCHEMBL3919212 0.97 DPP4 (0.48) DPP4F2HTR2ATAAR1ADRA2A
Water SCHEMBL5430575 0.97 DPP4 (0.48) DPP4F2HTR2ATAAR1ADRA2A
Hydrochloric Acid SCHEMBL11329469 0.95 DPP4 (0.46) DPP4F2HTR2ATAAR1ADRA2A
Hydrochloric Acid SCHEMBL28317319 0.95 DPP4 (0.46) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL6291617 0.86 ADRB2 (0.31) DPP4F2
SCHEMBL9256933 0.82 DPP4 (0.36) DPP4F2HTR2A
SCHEMBL5687743 0.77 MEN1 (0.40) HIF1AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5605 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684875-A Temperature-resistant high-strength powder coating and preparation method thereof 广东普科特粉末涂料有限公司 2025-03-25 CN claimed
WO-2024030977-A2 NOVEL MELANOCORTIN ANALOGS SIGHTSTREAM BIOTHERAPEUTICS, INC. (US) 2024-02-08 WO claimed
CN-117480223-A Coating for marine vessels to reduce cavitation 石墨创新技术有限公司 2024-01-30 CN claimed
CN-117101725-A Immobilized manganese catalyst and preparation method and application thereof 浙江工业大学 2023-11-24 CN claimed
CN-117042473-A Perovskite solar cell and preparation method and application thereof 深圳现象光伏科技有限公司 2023-11-10 CN claimed
US-20230330188-A1 PHARMACEUTICAL COMBINATION FOR USE IN THE TREATMENT AND/OR PREVENTION OF DIABETES INSPHERO AG (CH) 2023-10-19 US claimed
EP-4225296-A1 PHARMACEUTICAL COMBINATION FOR USE IN THE TREATMENT AND/OR PREVENTION OF DIABETES Insphero AG (CH) 2023-08-16 EP claimed
CN-116600799-A Pharmaceutical combination for the treatment and/or prophylaxis of diabetes 银丝佛若有限公司 2023-08-15 CN claimed
EP-4223317-A2 MODULATION OF COMPLEMENT ACTIVITY RA Pharmaceuticals, Inc. (US) 2023-08-09 EP claimed
EP-3401369-B1 PROCESS FOR MAKING AN ANTI-REFLECTIVE COATING COMPOSITION AND A POROUS COATING MADE THEREFROM COVESTRO NETHERLANDS BV (NL) 2023-07-19 EP claimed
EP-0002604-B1 QUATERNARY AMMONIUM SALTS, AND THEIR FORMULATIONS AND PREPARATION ELI LILLY AND COMPANY (US) 1983-05-04 EP claimed
EP-0023631-B1 MEANS AND METHOD FOR DETERMINING THE IONIC STRENGTH OR SPECIFIC GRAVITY OF AN AQUEOUS TEST SAMPLE MILES LABORATORIES, INC. (US) 1983-02-16 EP claimed
US-4340522-A Process for preparing cationic polymers POLAROID CORPORATION (US) 1982-07-20 US claimed
US-4339616-A AMINE SALTS AS CATALYSTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1982-07-13 US claimed
EP-0023578-A1 Aminoalkylbenzene derivatives, process for their preparation and pharmaceutical compositions SHIONOGI & CO., LTD. (JP) 1981-02-11 EP claimed
US-4240450-A HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS L'OREAL (FR) 1980-12-23 US claimed
US-4220450-A Chemically induced fluorescence immunoassay SYVA COMPANY (US) 1980-09-02 US claimed
US-4157387-A Dentifrice composition containing an abrasive coated with a cationic water soluble polymer THE PROCTER & GAMBLE COMPANY (US) 1979-06-05 US claimed
US-4110083-A HARD MINERAL PARTICLES COATED WITH A CATIONIC WATER-SOLUBLE POLYMER THE PROCTER & GAMBLE COMPANY (US) 1978-08-29 US claimed
US-3992307-A BIS-PHOSPHORAMIDE CHEVRON RESEARCH COMPANY (US) 1976-11-16 US claimed