Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3874231

CC#CCn1c(=O)n(CCC)c2nc(OC)nc(N3CCNCC3)c21.O=C(O)C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 16/20 0.42
FAP Q12884 6/20 0.39
DPP9 Q86TI2 1/20 0.35
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
ATP6V1B2 P21281 1/20 0.33
TBXA2R P21731 1/20 0.33
EDNRA P25101 1/20 0.33
TARBP2 Q15633 1/20 0.33
PIM1 P11309 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3879651 0.95 DPP4 (0.43) DPP4FAPDPP9
Trifluoroacetic Acid SCHEMBL3876200 0.92 DPP4 (0.51) DPP4FAPDPP9
SCHEMBL13866924 0.92 DPP4 (0.48) DPP4FAPDPP9PIM1
Trifluoroacetic Acid SCHEMBL3875531 0.89 DPP4 (0.39) DPP4FAPDPP9
Trifluoroacetic Acid SCHEMBL3875611 0.89 DPP4 (0.39) DPP4FAPDPP9
Trifluoroacetic Acid SCHEMBL3875820 0.88 DPP4 (0.43) DPP4FAPDPP9LMNACYP2C9
SCHEMBL13866916 0.86 DPP4 (0.49) DPP4FAPDPP9
Trifluoroacetic Acid SCHEMBL3885858 0.85 DPP4 (0.49) DPP4FAPDPP9
Trifluoroacetic Acid SCHEMBL3878348 0.85 DPP4 (0.42) DPP4FAPDPP9
Trifluoroacetic Acid SCHEMBL3888333 0.85 DPP4 (0.43) DPP4FAPDPP9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524847-B2 Fused 1,3-dihydro-imidazole ring compounds EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-04-28 US disclosed
US-20060111362-A1 1,3-Dihydroimidazole ring compound EISAI CO., LTD. (JP) 2006-05-25 US disclosed
EP-1568699-A1 1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND Eisai Co., Ltd. (JP) 2005-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111362-A1 1,3-Dihydroimidazole ring compound NR2C2, NR0B2, DPP4 DPP4 3/4885FAP 4451/4885DPP9 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.