SCHEMBL387432

SCHEMBL387432

Nc1noc(N)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003977 0.73 RECQL (0.58)
SCHEMBL20433304 0.69
SCHEMBL900321 0.69
SCHEMBL900320 0.69
SCHEMBL19633160 0.69
SCHEMBL21792056 0.69
SCHEMBL18937731 0.69
SCHEMBL1389077 0.69
SCHEMBL10741341 0.69
SCHEMBL1389025 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007077333-A2 USE OF A NEUROPEPTIDE Y ANTAGONIST FOR DAMAGED OR SENSITIVE LIPS L'OREAL (FR) 2007-07-12 WO claimed
EP-0680469-B1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME BOEHRINGER INGELHEIM PHARMA (DE) 2000-04-26 EP claimed
US-5807875-A OBESITY THERAPY DR. KARL THOMAE GMBH (DE) 1998-09-15 US claimed
EP-0044266-B1 SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLES AND 3,5-DIAMINO-1,2,4-THIADIAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Beiersdorf Aktiengesellschaft (DE) 1985-09-18 EP claimed
EP-0044266-A2 Substituted 3,5-diamino-1,2,4-oxadiazoles and 3,5-diamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them Beiersdorf Aktiengesellschaft (DE) 1982-01-20 EP claimed
JP-57032274-A None JP disclosed
CN-121449620-A Triazolo-tetrazine derivative and preparation method and application thereof 中国科学院过程工程研究所 2026-02-03 CN disclosed
WO-2017076740-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2017-05-11 WO disclosed
EP-2356113-B1 HETEROCYCLICALLY SUBSTITUTED ARYL COMPOUNDS AS HIF INHIBITORS BAYER IP GMBH (DE) 2015-01-07 EP disclosed
WO-2013059278-A2 HEPATITIS C VIRUS INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2013-04-25 WO disclosed
US-20120077812-A1 BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS FANG JING (US) 2012-03-29 US disclosed
US-8101634-B2 Bicyclic compounds and use as antidiabetics GLAXOSMITHKLINE LLC (US) 2012-01-24 US disclosed
EP-0044266-B1 SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLES AND 3,5-DIAMINO-1,2,4-THIADIAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Beiersdorf Aktiengesellschaft (DE) 1985-09-18 EP disclosed
EP-0044266-B1 SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLES AND 3,5-DIAMINO-1,2,4-THIADIAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Beiersdorf Aktiengesellschaft (DE) 1985-09-18 EP disclosed
EP-0114850-A1 NEW SUBSTITUTED DERIVATIVES OF 2,5-DIAMINO 1,4-DIAZOLE, PREPARATION METHODS THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. BOUCHARA EMILE (FR) 1984-08-08 EP disclosed
WO-1984000546-A1 NEW SUBSTITUTED DERIVATIVES OF 2,5-DIAMINO 1,4-DIAZOLE, PREPARATION METHODS THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOUCHARA EMILE (FR) 1984-02-16 WO disclosed
JP-S5732274-A SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLE AND 3,5-DIAMINO-1,2,4-THIADIAZOLE, MANUFACTURE AND USE THEREOF BEIERSDORF AG 1982-02-20 JP disclosed
EP-0044266-A3 SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLES AND 3,5-DIAMINO-1,2,4-THIADIAZOLES, THEIR PREPARATION AND USE 1982-02-03 EP disclosed
EP-0044266-A2 Substituted 3,5-diamino-1,2,4-oxadiazoles and 3,5-diamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them Beiersdorf Aktiengesellschaft (DE) 1982-01-20 EP disclosed
EP-0044266-A2 Substituted 3,5-diamino-1,2,4-oxadiazoles and 3,5-diamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them Beiersdorf Aktiengesellschaft (DE) 1982-01-20 EP disclosed