Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 8/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385878 | 0.88 | FAAH (0.35) | CES1FAAHCTSKSIGMAR1DAGLA | |
| SCHEMBL386964 | 0.82 | FAAH (0.38) | CES1FAAHCTSKSIGMAR1DAGLA | |
| SCHEMBL387356 | 0.81 | CES1 (0.41) | CES1FAAHSIGMAR1DAGLA | |
| SCHEMBL387454 | 0.77 | CES1 (0.38) | CES1FAAHSIGMAR1DAGLA | |
| SCHEMBL3185558 | 0.72 | FAAH (0.39) | CES1FAAH | |
| SCHEMBL3185556 | 0.72 | FAAH (0.39) | CES1FAAH | |
| SCHEMBL386667 | 0.72 | CES1 (0.42) | CES1FAAHSIGMAR1DAGLA | |
| SCHEMBL385877 | 0.71 | FAAH (0.37) | CES1FAAHSIGMAR1 | |
| SCHEMBL386686 | 0.71 | S1PR1 (0.43) | CES1FAAHCTSKSIGMAR1DAGLA | |
| SCHEMBL386963 | 0.69 | FAAH (0.36) | CES1FAAHCTSKSIGMAR1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101650-B2 | Method for treating a immunology-related disease | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8067396-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2011-11-29 | — | — | US | disclosed |