⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886205 | 1.00 | — | — | |
| SCHEMBL486112 | 1.00 | — | — | |
| SCHEMBL7716652 | 0.93 | MEN1 (0.41) | — | |
| SCHEMBL9354384 | 0.93 | MEN1 (0.41) | — | |
| SCHEMBL6553029 | 0.82 | — | — | |
| SCHEMBL65810 | 0.80 | — | — | |
| SCHEMBL8846056 | 0.80 | — | — | |
| SCHEMBL2739848 | 0.80 | — | — | |
| SCHEMBL5979280 | 0.80 | — | — | |
| SCHEMBL5344482 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536329-B1 | R(+)-TERAZOSIN | ABBOTT LAB (US) | 1996-04-17 | — | — | EP | claimed |
| EP-1345910-B9 | QUINAZOLINE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THEIR UTILIZATION AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA (DE) | 2014-06-04 | — | — | EP | disclosed |
| EP-2010185-B1 | DIHYDROTHIENOPYRIMIDINE FOR TREATING INFLAMMATORY DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2012-06-13 | — | — | EP | disclosed |
| EP-2112140-A1 | Chinazolin derivatives, medicine containing these compounds, application thereof and method for their production | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-1345910-B1 | QUINAZOLINE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THEIR UTILIZATION AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-04-29 | — | — | EP | disclosed |
| WO-2009034029-A2 | 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |
| EP-2010185-A1 | DIHYDROTHIENOPYRIMIDINE FOR TREATING INFLAMMATORY DISORDERS | Boehringer Ingelheim International GmbH (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007118793-A1 | DIHYDROTHIENOPYRIMIDINE FOR TREATING INFLAMMATORY DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-25 | — | — | WO | disclosed |
| EP-1345910-A1 | QUINAZOLINE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THEIR UTILIZATION AND METHOD FOR THE PRODUCTION THEREOF | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050043-A1 | QUINAZOLINE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THEIR UTILIZATION AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-06-27 | — | — | WO | disclosed |
| EP-0521496-B1 | Process for producing optically active carboxylic acids | CONSORTIUM ELEKTROCHEM IND (DE) | 1994-10-19 | — | — | EP | disclosed |
| EP-0521496-A2 | Process for producing optically active carboxylic acids | Consortium für elektrochemische Industrie GmbH (DE) | 1993-01-07 | — | — | EP | disclosed |
| EP-0355561-B1 | USE OF OPTICALLY ACTIVE TETRAHYDROFURAN-2-CARBOXYLIC-ACID ESTERS IN DOPING LIQUID-CRYSTAL MIXTURES, LIQUID-CRYSTAL MIXTURES CONTAINING THEM, AND OPTICALLY ACTIVE TETRAHYDROFURAN-2-CARBOXYLIC-ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0355561-A1 | Use of optically active tetrahydrofuran-2-carboxylic-acid esters in doping liquid-crystal mixtures, liquid-crystal mixtures containing them, and optically active tetrahydrofuran-2-carboxylic-acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |