⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976692 | 1.00 | — | — | |
| SCHEMBL5283278 | 0.81 | SLC7A5 (0.46) | — | |
| SCHEMBL10623519 | 0.79 | USP2 (0.50) | — | |
| SCHEMBL29957453 | 0.78 | SLC7A5 (0.62) | — | |
| SCHEMBL25933046 | 0.78 | SLC7A5 (0.62) | — | |
| SCHEMBL1007447 | 0.78 | SLC7A5 (0.62) | — | |
| SCHEMBL468084 | 0.78 | SLC7A5 (0.62) | — | |
| SCHEMBL600021 | 0.78 | SLC7A5 (0.62) | — | |
| SCHEMBL21598894 | 0.78 | SLC7A5 (0.48) | — | |
| SCHEMBL27788945 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | claimed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | claimed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | claimed |
| EP-0750489-B1 | INHIBITION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1998-11-18 | — | — | EP | claimed |
| US-5455234-A | Applying inhibitor of cysteine pathway enzyme topically to skin; cosmetic for face, arms, legs | AHLUWALIA GURPREET S (US) | 1995-10-03 | — | — | US | claimed |
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | disclosed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | disclosed |
| EP-1656095-A4 | N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES | NOVACAL PHARMACEUTICALS INC (US) | 2007-11-28 | — | — | EP | disclosed |
| EP-1656095-A2 | N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES | NovaCal Pharmaceuticals, Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005020896-A2 | N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES | NOVACAL PHARMACEUTICALS, INC. (US) | 2005-03-10 | — | — | WO | disclosed |
| EP-0750489-B1 | INHIBITION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5455234-A | Applying inhibitor of cysteine pathway enzyme topically to skin; cosmetic for face, arms, legs | AHLUWALIA GURPREET S (US) | 1995-10-03 | — | — | US | disclosed |
| US-4966856-A | QUANTITATIVE ANALYSIS OF FLUID SAMPLES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4783443-A | Amino acyl cephalosporin derivatives | THE UNIVERSITY OF CHICAGO (US) | 1988-11-08 | — | — | US | disclosed |
| WO-1987005297-A1 | CEPHALOSPORIN DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 1987-09-11 | — | — | WO | disclosed |