SCHEMBL468084

SCHEMBL468084

N[C@H](C(=O)O)[C@@H](N)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.62
SLC1A3 P43003 5/20 0.50
SLC1A2 P43004 5/20 0.50
SLC1A1 P43005 5/20 0.50
USP2 O75604 1/20 0.46
SLCO1B1 Q9Y6L6 1/20 0.46
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42
GSR P00390 1/20 0.41
TSHR P16473 1/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.40
RECQL P46063 1/20 0.40
ACHE P22303 1/20 0.39
GRM2 Q14416 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957453 1.00 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL1007447 1.00 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL25933046 1.00 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL600021 1.00 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Hydrochloric Acid SCHEMBL11095114 0.96 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL4632980 0.96 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL4633860 0.96 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL28153656 0.89 SLC7A5 (0.53) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL3930054 0.86 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL5326967 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009018368-A1 COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) 2009-02-05 WO claimed
CN-119912365-A Taurine refining process and application thereof 江阴华昌食品添加剂有限公司 2025-05-02 CN disclosed
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis SHENZHEN JINGTAI TECHNOLOGY CO., LTD. (CN) 2025-01-23 US disclosed
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 EP disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP disclosed
EP-4426727-A2 SPECIFIC CONJUGATION OF AN ANTIBODY Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP disclosed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN disclosed
CN-118434765-A BCMA monoclonal antibodies and antibody-drug conjugates 杭州多禧生物科技有限公司 2024-08-02 CN disclosed
CN-118234705-A Aspartic acid derivative and application thereof in treatment of liver fibrosis, nonalcoholic hepatitis and other metabolic diseases 深圳利沃生物医药科技有限公司 2024-06-21 CN disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
WO-2003047558-A2 TREATMENT OF CNS DISORDERS USING D-AMINO ACID OXIDASE AND D-ASPARTATE OXIDASE INHIBITORS GENSET S.A. (FR) 2003-06-12 WO disclosed
WO-2002066672-A2 TREATMENT OF CNS DISORDERS USING D-AMINO ACID OXIDASE AND D-ASPARTATE OXIDASE ANTAGONISTS GENSET S.A. (FR) 2002-08-29 WO disclosed
EP-1009770-A1 PEPTIDES CONTAINING AN ARGININE MIMETIC FOR THE TREATMENT OF BONE METABOLIC DISORDERS, THEIR PRODUCTION, AND DRUGS CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 2000-06-21 EP disclosed
WO-1999012970-A1 PEPTIDES CONTAINING AN ARGININE MIMETIC FOR THE TREATMENT OF BONE METABOLIC DISORDERS, THEIR PRODUCTION, AND DRUGS CONTAINING THESE COMPOUNDS ROCHE DIAGNOSTICS GMBH (DE) 1999-03-18 WO disclosed
EP-0902036-A1 Peptide containing an arginine mimetic for the treatment of osteoporosis, their production, and drugs containing these compounds Roche Diagnostics GmbH (DE) 1999-03-17 EP disclosed
US-5695737-A CONTRAST MEDIA FOR NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1997-12-09 US disclosed
US-5610141-A CELL DIVISION STIMULANT NYCOMED IMAGING AS (NO) 1997-03-11 US disclosed
EP-0673388-A1 DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY NYCOMED IMAGING AS (NO) 1995-09-27 EP disclosed
US-5362477-A 19F magnetic resonance imaging agents which include a nitroxide moiety MALLINCKRODT MEDICAL, INC. (US) 1994-11-08 US disclosed
WO-1993024523-A1 DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY HAFSLUND NYCOMED AS (NO) 1993-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis GOT1, GOT2, GLS2 SLC7A5 210/4885SLC1A3 105/4885SLC1A2 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.