Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889371 | 0.93 | TRPV1 (0.45) | HSD11B1TRPV1 | |
| SCHEMBL3877901 | 0.93 | HSD11B1 (0.49) | HSD11B1TRPV1 | |
| SCHEMBL3879653 | 0.92 | HSD11B1 (0.45) | HSD11B1TRPV1 | |
| SCHEMBL3879568 | 0.92 | HSD11B1 (0.44) | HSD11B1 | |
| SCHEMBL3877002 | 0.92 | TRPV1 (0.44) | HSD11B1TRPV1 | |
| SCHEMBL3878926 | 0.90 | GALR2 (0.43) | HSD11B1 | |
| SCHEMBL3878946 | 0.90 | HSD11B1 (0.48) | HSD11B1TRPV1 | |
| SCHEMBL3882474 | 0.90 | HSD11B1 (0.48) | HSD11B1TRPV1 | |
| SCHEMBL3891329 | 0.89 | HSD11B1 (0.45) | HSD11B1TRPV1 | |
| SCHEMBL3877757 | 0.89 | HSD11B1 (0.43) | HSD11B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | claimed |
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |