SCHEMBL3876229

SCHEMBL3876229

CCC(C(=O)O)n1cccc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.55
HSD17B10 Q99714 1/20 0.55
PPARG P37231 5/20 0.42
MAPT P10636 4/20 0.41
TP53 P04637 2/20 0.41
PPARA Q07869 2/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.37
MAPK1 P28482 1/20 0.37
THRB P10828 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18258603 1.00 NPSR1 (0.55) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL5512388 0.83 NPSR1 (0.52) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL18258632 0.83 NPSR1 (0.52) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL18258597 0.82 NPSR1 (0.47) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL18258598 0.82 NPSR1 (0.47) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL3050045 0.80 CA1 (0.42) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL18258589 0.79 NPSR1 (0.49) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL18258587 0.79 NPSR1 (0.49) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL29180304 0.79 NPSR1 (0.57) NPSR1HSD17B10PPARGMAPTTP53
SCHEMBL2793671 0.79 NPSR1 (0.57) NPSR1HSD17B10PPARGMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119265552-A Chemical nickel-plating palladium-gold solution 生益电子股份有限公司 2025-01-07 CN claimed
CN-118185522-A Adhesive, preparation method and application thereof in lithium battery electrode 常熟市辐照技术应用厂 2024-06-14 CN claimed
CN-119265552-A Chemical nickel-plating palladium-gold solution 生益电子股份有限公司 2025-01-07 CN disclosed
CN-118185522-A Adhesive, preparation method and application thereof in lithium battery electrode 常熟市辐照技术应用厂 2024-06-14 CN disclosed
CN-118185522-A Adhesive, preparation method and application thereof in lithium battery electrode 常熟市辐照技术应用厂 2024-06-14 CN disclosed
CN-114217505-A Photoresist, display substrate and display panel 长沙惠科光电有限公司 2022-03-22 CN disclosed
US-10987408-B2 Compositions and methods for modulating toll-like receptor 2 activation THE CLEVELAND CLINIC FOUNDATION (US) 2021-04-27 US disclosed
US-20190069527-A1 MOUSE MODEL OF RETINAL DEGENERATION CLEVELAND CLINIC FOUNDATION 2019-03-07 US disclosed
US-20180280482-A1 COMPOSITIONS AND METHODS FOR MODULATING TOLL-LIKE RECEPTOR 2 ACTIVATION CLEVELAND CLINIC FOUND (US) 2018-10-04 US disclosed
US-20180160660-A1 MOUSE MODEL OF RETINAL DEGENERATION CLEVELAND CLINIC FOUNDATION 2018-06-14 US disclosed
US-9981018-B2 Compositions and methods for modulating toll-like receptor 2 activation THE CLEVELAND CLINIC FOUNDATION (US) 2018-05-29 US disclosed
WO-2008089487-A2 CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION THE CLEVELAND CLINIC FOUNDATION (US) 2008-07-24 WO disclosed
WO-2007127151-A2 NON-HUMAN MODEL OF AUTOIMMUNE DISEASE THE CLEVELAND CLINIC FOUNDATION (US) 2007-11-08 WO disclosed
EP-1451376-A2 A COATED FILM LAMINATE HAVING AN ELECTRICALLY CONDUCTIVE SURFACE 3M Innovative Properties Company (US) 2004-09-01 EP disclosed
US-20040115793-A1 COATED FILM LAMINATE HAVING AN ELECTRICALLY CONDUCTIVE SURFACE 3M INNOVATIVE PROPERTIES COMPANY 2004-06-17 US disclosed
WO-2003106962-A2 A COATED FILM LAMINATE HAVING AN ELECTRICALLY CONDUCTIVE SURFACE 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-12-24 WO disclosed
EP-0887353-B1 Luminescence indicator HOFFMANN LA ROCHE (CH) 2003-08-20 EP disclosed
US-5981746-A Luminescence indicator AVL MEDICAL INSTRUMENTS (CH) 1999-11-09 US disclosed
EP-0887353-A2 Luminescence indicator AVL Medical Instruments (CH) 1998-12-30 EP disclosed
US-4148998-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10987408-B2 Compositions and methods for modulating toll-like receptor 2 activation TLR2, TLR3, TLR1 NPSR1 484/4885HSD17B10 2405/4885PPARG 270/4885
US-20180280482-A1 COMPOSITIONS AND METHODS FOR MODULATING TOLL-LIKE RECEPTOR 2 ACTIVATION TLR2, TLR3, TLR1 NPSR1 484/4885HSD17B10 2405/4885PPARG 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.