Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222217 | 0.85 | F10 (0.69) | F10F2KLK1 | |
| SCHEMBL3873832 | 0.83 | F10 (0.65) | F10F2KLK1 | |
| SCHEMBL3873911 | 0.83 | F10 (0.72) | F10F2KLK1 | |
| SCHEMBL3881131 | 0.82 | F10 (0.55) | F10F2KLK1 | |
| SCHEMBL3872859 | 0.73 | F10 (0.58) | F10F2 | |
| SCHEMBL3879178 | 0.72 | F10 (0.60) | F10 | |
| SCHEMBL220661 | 0.71 | F10 (0.89) | F10 | |
| SCHEMBL3879613 | 0.71 | F10 (0.59) | F10 | |
| SCHEMBL219798 | 0.71 | F10 (1.00) | F10 | |
| SCHEMBL221783 | 0.70 | F10 (0.71) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | claimed |