Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 19/20 | 0.75 |
| ▸ | RARB | P10826 | 10/20 | 0.75 |
| ▸ | RARA | P10276 | 9/20 | 0.75 |
| ▸ | RXRA | P19793 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877740 | 0.98 | RARG (0.73) | RARGRARBRARARXRA | |
| SCHEMBL344736 | 0.90 | RARG (0.60) | RARGRARBRARARXRA | |
| SCHEMBL345649 | 0.88 | RARG (0.58) | RARGRARBRARARXRA | |
| SCHEMBL345684 | 0.86 | RARG (1.00) | RARGRARBRARARXRA | |
| SCHEMBL5846405 | 0.85 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL5846253 | 0.85 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL5845369 | 0.85 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL5845781 | 0.85 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL955323 | 0.85 | RARG (0.83) | RARGRARBRARARXRA | |
| SCHEMBL5847036 | 0.85 | RARG (0.98) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963250-B1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTOR | GALDERMA RES & DEV (FR) | 2009-09-09 | — | — | EP | disclosed |
| EP-1963250-A1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTOR | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007068580-A1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTOR | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-06-21 | — | — | WO | disclosed |